So to avoid any of these causes of hives, it’s important to know your allergy triggers. Keep a journal of things that cause reactions so that you will remember to avoid them in the future. And if you find something to which you might be allergic, consult your doctor. Doctors often can prescribe tests that will confirm suspicions.

2.    Take Antihistamines

Antihistamines are common medications that can be purchased over the counter. Antihistamines block histamines, which cause hives.

Just make sure you don’t take an antihistamine that will make you sleepy.  To avoid this, the Mayo Clinic suggests starting with what’s known as a “second-generation antihistamine.” That’s because these medications come with fewer side effects like drowsiness. Examples of second-generation antihistamines include Loratadine (Claritin, Alavert), Fexofenadine (Allegra), Cetirizine (Zyrtec), Levocetirizine (Xyzal) and Desloratadine (Clarinex).

If these don’t work, you can switch to a classic antihistamine. However, try to take these meds at bedtime as they can interfere with work performance or driving. The Mayo Clinic says that these medications include: Hydroxyzine (Vistaril), Diphenhydramine (Benadryl), and Chlorpheniramine (Chlor-Trimeton).

3.    Calamine Lotion

Calamine lotion does a good job of relieving itching associated with hives. This nonprescription remedy can be found in the form of ointments, lotions and creams. Witch hazel is another option. Both can relieve that all-over-uncomfortable feeling.

4.    Cool the Skin

Cooling the skin is key to dealing with hives. That’s because cooling shrinks blood vessels, which, in turn, blocks histamines.