Clarkson’s Disease
According to the Mayo Clinic, systemic capillary leak syndrome, also called Clarkson’s disease, “is a rare disorder characterized by recurrent flares of massive leakage of plasma and other blood components from blood vessels into neighboring body cavities and muscles.”
The result of this leakage is swelling. “The symptoms result from a sudden and unexplained increase in the leakiness of small blood vessel (capillary) walls,” according to the Mayo Clinic. “Unless treated, massive fluid shifts result in a sharp drop in blood pressure that can lead to organ failure and death.”
Symptoms of Clarkson’s disease include sudden swelling, a quick drop in blood pressure, shock, dizziness or lightheadedness, a feeling of weakness and nausea.
In truth, it’s not known why Clarkson’s disease occurs. However, it is thought that this health condition sometimes can be caused by an upper respiratory tract infection, which triggers it.
Blood and urine tests are used to diagnose this condition. These tests may reveal excess amounts of red blood cells from plasma leakage. Decreased amounts of the protein albumin may be found. And doctors will look for a protein called monoclonal protein that can signify the disease.